Signe Rigney

Author Archives: Signe Rigney

What is host modulated therapy and what are my options?

The pursuit to effectively control the chronic inflammation in the gums should “err on the side of aggressive” according to top periodontal researchers.  What does this mean?

For some clinicians it may mean more aggressive treatment plans including surgery or extractions.  But in much of the recent periodontal literature it means incorporating “host modulated therapy”, or medication, to suppress chronic inflammatory response.

Host modulated therapy medication works by down-regulating the inflammatory cascade mechanism internally, changing how the body reacts to bacteria and other unbalanced conditions; thereby restoring equilibrium and health.

Cause of Chronic Periodontal Inflammation

Periogain balances your immune system, restoring equilibrium in the gums. Our extensive professional experience in treating all stages of gum disease successfully led to the discovery of our innovative dental supplement.

Periogain contains 6 powerful anti-inflammatory and antioxidant nutriceuticals  that specifically target the inflammation associated with all stages of periodontal disease. Periogain reduces inflammation naturally and is intended to be taken adjunctively with professional care.

Less inflammation…less bone loss…less tooth loss…better health!

 Periogain has been clinically shown to effectively and safely reduce:

  • Inflammation in the Gums
  • Bleeding Gums
  • Gum Disease Treatment
  • Deep Gum Pockets
  • Mobility of Teeth
  • Tooth Abscess
  • Pussy Gums

Periogain used in conjunction with Professional Gum Treatments

After researching and incorporating a prescription drug called Periostat(TM) for over a decade, she was convinced of the remarkable benefits of addressing the inflammatory response systemically. Even though side effects were rare with low dose doxycycline (Periostat), Ms. Carroll was determined to find and offer a more natural choice… Periogain was born.

The clinical results observed with all natural Periogain are nothing short of extraordinary in our experience. Periogain effectively down-regulates the harmful enzymes and chronic inflammation associated with all forms of gum disease.   Periogain also  promotes healing and regeneration with the addition of powerful antioxidants.  We encourage you to seek professional advice from a periodontist or dentist regarding your gum disease. We also invite you to try our innovative product and write to us to share your success story.

The answer is in the six ingredients in Periogain, and the specific dosing of each herb.  A quick search on any of the ingredients in Periogain and you are inundated with hundreds of overall health benefits.  However, we were determined to formulate Periogain to be optimally beneficial specifically for issues in periodontal disease by down-regulating harmful enzymes and providing optimal antioxidants to restore equilibrium.

with Periogain – A Natural Dental Supplement

If you have been diagnosed with periodontal disease, or you think you may have periodontal disease, it is important to find out what is causing the chronic inflammation which leads to bleeding and swollen or red gums, receding of the gums, bone loss, halitosis, and shifting or loose teeth.  Often, chronic and destructive periodontal inflammation is painless, so it may not be diagnosed until it has reached the advanced stages.

For some clinicians it may mean a more aggressive treatment plan including surgery and extractions.  Or it may mean using potent short term antibiotics.  But in our view it means incorporating a cutting edge approach called ”host modulated therapy” into the equation to down-regulate chronic inflammatory response. It has been estimated that over 5 billlion people worldwide are afflicted with some form of gum disease.  Are you one of them?  Treat your gum disease with effective, all-natural Periogain, the latest innovation from Life Changing Formulations.

Gum Disease

Created and clinically tested by dental professionals, Periogain will tighten your gums to ward off gum disease and may even prevent the need for gum surgery. Contact us to learn more about our affordable and effective gum disease treatment that is all natural.

Your mouth can say a lot about your overall health. Did you know gum disease has been connected to other life-threatening diseases? A visit to the dentist may not be enough. Researchers have discovered that gum disease is not only caused by plaque and tartar, but more importantly, your immune system.

That’s right, how your body responds to bacteria is actually what causes swelling, bleeding, deep gum pockets, bone loss, and even halitosis (bad breath). We offer a new perspective for the successful treatment of periodontal disease by addressing and targeting the cause – inflammation.

Fight Gum Disease

Researchers have determined that the real cause of periodontal breakdown is chronic inflammation.  But what causes this chronic, harmful inflammation?

It used to be thought that periodontal disease was simply caused by the presence of bacteria creating chronic or acute infection in the gums.  While it is true that certain bacteria do trigger inflammation and infection, these pathogens (harmful bacteria) are not the only cause of chronic inflammation.

Depleted hormone levels (including thyroid), pregnancy, menopause, ingesting birth control pills, dry mouth (xerostomea), nutritional deficiencies, smoking, a diet high in refined carbohydrates or sugar, obesity (fat cells promote inflammation throughout the body), incomplete or non-existant dental cleanings, poor home care, and stress.

Help Your Patients Keep Their Gums Pain-Free

    Take one to two capsules twice daily.  For optimal benefit Periogain should be started one week before periodontal treatment is initiated, and continued for three months following treatment to promote optimal healing.  If challenging risk factors are an issue, we recommend a maintenance dose of one to two capsules twice daily.  Risk factors would include smoking, genetic predisposition for advanced periodontal disease, diabetes or other systemic challenges.

    Periogain should not be taken if you are pregnant or nursing, or if you are intending to become pregnant.

    Patients taking blood thinners need to check with their physician before taking Periogain.  INR (clotting time) will need to be monitored, just as with taking Periostat or low dose doxycycline.

As professionals in the dental industry, we here at Life Changing Formulations, LLC want to encourage our customers to seek out professional care for their gum disease.  We understand that many individuals are afraid or even embarrassed about going to the dentist.  For this reason we would like to extend an invitation for you to call us directly to help ease your mind.  We can also help you sort through all the confusing information.  Call us today!

What professional periodontal treatment options are available to help my gums?

Traditional Approaches to helping to restore health in diseased gums include:

    Traditional maintenance cleanings

    Traditional root planing (deep cleanings), with or without systemic or locally applied antibiotics

    Traditional periodontal (gum) surgery to reduce deep gum pockets

More advanced periodontal treatment options available:

    Minimally Invasive Periodontal Surgery


    Regenerative Periodontal Endoscopy – RPE

Periogain used in conjunction with Professional Gum Treatments

Attention: Dentists and Hygienists

If you have ever struggled with periodontal disease, or have been told that you need gum surgery, extractions of teeth, or frequent deep cleanings, we invite you to explore the important and enlightening information contained within our site.   Knowledge is empowering!   The information here may very well change your life.

It has been estimated that 5 billion people worldwide are afflicted with some form of gum disease.  Options for the effective treatment of this worldwide epidemic are limited, and are often ineffective or expensive.

  Our mission at Life Changing Formulations, LLC  is to empower anyone suffering from chronic periodontal disease to better manage their disease, and to avoid painful gum surgery, tooth loss, or repetative treatments.   It is also our mission to educate all professionals about chronic gum inflammation and how it can be effectively addressed.

Enhanced periodontal and overall health can be achieved in a natural, yet highly effective and affordable way.  Let us show you how.

Developing a Natural Alternative

Periodontal disease progression can be preventable with our innovative periodontal supplement – Periogain. Periogain helps your patients gums by down-regulating the chronic inflammatory response and promoting health with powerful antioxidants – thereby restoring equilibrium and aiding in tissue repair.

Periogain may be an excellent natural and effective alternative to Periostat, or SDD (sub-antimicrobial dose doxycycline) by helping to down regulate harmful enzymes. We are looking to provide this innovative supplement to people across the world to help them treat periodontal disease from the inside out. Periodontal disease is often chronic and can have a variety of challenging host factors – our natural alternative helps your patients manage it daily.

At Life Changing Formulations, we offer Periogain at wholesale prices so you can offer it to your patients. Now you finally have an alternative periodontal disease treatment option which will modify host response safely and effectively for your patients in all stages of periodontal disease. You wont be disappointed in the effectiveness of our innovative product.  We would appreciate feedback about clinical results and observations.

After years of research and working with hundreds of advanced cases, our patients encouraged us to develop a natural dental supplement to modify or down-regulate chronic inflammatory host response. Synthetic periodontal disease treatments such as Periostat™, although very effective, may not be generally well received by patients due to cost or difficulty in taking due to diet restrictions. Periogain may be an effective alternative, yet it is all natural and affordable.

Periodontal Treatment

We highly recommend that all periodontal sufferers seek out the advice of a periodontist or dentist for their condition to undergo proper diagnosis and to discuss all treatment options.

Periogain is intended to be an adjunct to ongoing professional treatments and preventative periodontal maintenance care.Periogain was developed by a passionate dental hygienist committed to the advancement of minimally invasive gum disease treatment.

Ms. Carroll’s 20 years of clinical experience allowed her to directly observe the effects of all traditional gum disease treatment options. Unsatisfied, she set out to find a better non surgical solution to help her patients keep their teeth.